The Comfort Inn, Greenville SC is located just half a mile from the New Millennium Campus and the Clemson University International Center for Automotive Research and CU ICAR. Our Hotel is NEW to the Comfort Inn Family of hotels and we offer you the BEST in Accommodations, Hospitality, and Comfort. If you are visiting our area, our hotel is centrally located and we provide printed directions to all major points of interest. If you are traveling and looking for a resting point, look no further, we are an easy on and easy off location from I-85 at exit 48B.